The use of Promethazine HCl Oral Solution should be avoided in pediatric patients whose signs and symptoms may suggest Reye's syndrome or other hepatic diseases. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Medically reviewed by Drugs.com. 1, FD&C Red No. Your risk of this is higher if you have or are using chemotherapy that affects your bone marrow.
An increase in blood glucose has been reported in patients receiving Promethazine HCl. Respiratory depression, nightmares, delirium, and agitated behavior have also been reported in some of these patients. The effect on later growth and development of the newborn is unknown. Respiratory Depression in Children The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients less than 6 years of age. Hyperexcitability and abnormal movements have been reported in patients following a single administration of Promethazine HCl. Promethazine / codeine is a combination of two medications: promethazine and codeine. Drinking alcohol while taking promethazine / codeine raises your risk of side effects like drowsiness and dizziness. 2023 Par Pharmaceutical. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. The primary component is Promethazine Hydrochloride.
A household teaspoon is not an accurate measuring device and could lead to overdosage, especially when a half a teaspoon is measured. Bottles of promethazine codeine cough syrup produced by Hi-Tech Pharmaceuticals Inc. and Wockhardt Ltd. subsidiary Morton Grove Pharmaceuticals Inc. sell on the streets of Houston for $750 to. Par Pharmaceutical specializes in modified-released oral solid dosage forms as well as non-oral dosage forms, such as nasal sprays, inhalers, patches and other alternative drug delivery platforms. Promethazine / codeine is not recommended for use in children under 18 years old. Gastrointestinal-Dry mouth, nausea, vomiting, jaundice. Excessive amounts of promethazine HCl relative to a narcotic may lead to restlessness and motor hyperactivity in the patient with pain; these symptoms usually disappear with adequate control of the pain. Risk factors: Personal or family history of substance abuse | History of mental illness. Phenylephrine with tricyclic antidepressants. Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate, Losartan Potassium and Hydrochlorothiazide, Oxycodone Hydrochloride and Acetaminophen, NPI Look-Up Tool (National Provider Identifier), Generics Bidco I, LLC dba Qualitest Pharmaceuticals. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Promethazine HCl may be used alone or as an adjunct to narcotic analgesics during labor (see DOSAGE AND ADMINISTRATION). PAR promethazine with codeine is a purple syrup and Hi-Tech promethazine with codeine is a red syrup. PROMETHAZINE PRODUCTS ARE CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE. We offer high-quality, cost-effective products with the highest level of customer service.
EffectCardiac pressor response potentiated. Available as a lower-cost generic medication. Rx Only. Because of the potential for Promethazine to reverse epinephrine's vasopressor effect, epinephrine should NOT be used to treat hypotension associated with Promethazine HCl Oral Solution overdose. Drug Select the Trade Name to see similar products. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (e.g., pneumonia, systemic infection, etc.) Promethazine HCl, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N, -trimethyl-, monohydrochloride, ()- with the following structural formula: Promethazine HCl occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. Acidosis and electrolyte losses should be corrected. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. (See WARNINGS Promethazine; Respiratory Depression. If this worries you, talk to your doctor or pharmacist about other options. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Promethazine Hydrochloride Oral Solution, USP Excessively large dosages of antihistamines, including promethazine hydrochloride, in pediatric patients may cause sudden death (see OVERDOSAGE). Promethazine HCl Oral Solution may lead to potentially fatal respiratory depression. Products with assigned NDCs are displayed. Caution should be exercised when administering Promethazine HCl Oral Solution to pediatric patients 2 years of age and older because of the potential for fatal respiratory depression. (See WARNINGS Promethazine; Neuroleptic Malignant Syndrome.). Phenylephrine has a mild central stimulant effect.
Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients. Learn how to get the most out of your subscription. It is recommended to use promethazine / codeine at the lowest possible dose for the shortest period of time needed. codes diagnosis. 16 fl oz (473 mL) We have already encountered some chemical formulas for simple ionic compounds. Drowsiness is the most prominent CNS effect of this drug. Make sure your provider knows all medical conditions you have before taking promethazine / codeine. Respiratory Depression Promethazine may lead to potentially fatal respiratory depression. For preoperative medication, children require doses of 0.5 mg per pound of body weight in combination with an appropriately reduced dose of narcotic or barbiturate and the appropriate dose of an atropine-like drug. If you are using this medication for 5 days and don't feel any better, contact your provider to discuss alternatives.
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Of anesthesia and surgery as an adjunct to narcotic analgesics during labor ( see promethazine... Oral Solution may lead to potentially fatal ) and apnea ( potentially fatal ) apnea!Drug [49] Today, bromine is transported in large-capacity metal drums or lead-lined tanks that can hold hundreds of kilograms or even tonnes of bromine. Promethazine is metabolized by the liver to a variety of compounds; the sulfoxides of Promethazine and N-demethylPromethazine are the predominant metabolites appearing in the urine. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. This is called Addison's disease or adrenal insufficiency. They both contain the same dose of active ingredients promethazine hydrochloride/codeine phosphate 6.25mg-10mg/5mL syrup. Daily doses of 25 mg/kg intraperitoneally have been found to produce fetal mortality in rats. Patients should be advised to report any involuntary muscle movements. It is soluble in water and freely soluble in alcohol. Although not all of these side effects may occur, if they do occur they may need medical attention. Last updated on Nov 14, 2022.
Acidosis and electrolyte losses should be corrected. Without the right amount of these hormones, your body can't fight off infections properly. Dosage must be individualized. Promethazine VC by is a Prescription medication manufactured, distributed, or labeled by Par Pharmaceutical. When given concomitantly with Promethazine HCl Oral Solution, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. Thank you for choosing Find-A-Code, please Sign In to remove ads. Industry: Other Food Manufacturing , Fruit and Vegetable Preserving and Specialty Food Manufacturing , Grain and Oilseed Milling , Sugar and Confectionery Product Manufacturing , Beverage Manufacturing See All Industries, Pharmaceutical and Medicine Manufacturing , Grocery and Convenience Retailers , Food preparations, nec, Fruit juices: fresh, Canned fruits and specialties, Margarine and . Promethazine was nonmutagenic in the Salmonella test system of Ames. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Speak with your provider about safer medications for treating cold and allergy symptoms while you're pregnant. If you notice any other effects, check with your healthcare professional. Promethazine should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression. Respiratory-Asthma, nasal stuffiness, respiratory depression (potentially fatal) and apnea (potentially fatal). Promethazine and phenylephrine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Par Pharmaceutical Promethazine Hydrochloride by Drug Facts Promethazine Hydrochloride by is a Prescription medication manufactured, distributed, or labeled by Par Pharmaceutical. Manufacturer Name Healthfirst (1) Hikma Pharmaceuticals USA (3) Alternate Packaging . PARPHARM.COM 2023 Par Pharmaceutical. Preoperative, postoperative, or obstetric sedation. Thumbnail; . Only in cases of extreme overdosage or individual sensitivity do vital signs including respiration, pulse, blood pressure, temperature, and EKG need to be monitored. Product ID: 0603-1584_153678e2-0b91-4267-a9b9-e0a9913a98a3: NDC: 0603-1584: Product Type: Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. Tell your provider right away if you notice any unusual body movements. The average effective dose of Promethazine for the active therapy of nausea and vomiting in children or adults is 25 mg. Our focus is on therapeutically equivalent ANDA-based products, and others on a case-by-case basis. Symptoms of EPS include tremors, jerky movements of your arms or legs while walking, trouble swallowing or talking, and tongue thrusting. Promethazine / codeine can cause a life-threatening condition called Neuroleptic Malignant Syndrome (NMS).